23 citations · 55 across the 3 of their papers we have counts for
3 papers
A Bayesian seamless phase I-II trial design with two stages for cancer clinical trials with drug combinations
José L. Jiménez, Sungjin Kim, Mourad Tighiouart
The use of drug combinations in clinical trials is increasingly common during the last years since a more favorable therapeutic response may be obtained by combining drugs. In phas…
Properties of the weighted log-rank test in the design of confirmatory studies with delayed effects
Jose L Jimenez, Viktoriya Stalbovskaya, Byron Jones
Proportional hazards are a common assumption when designing confirmatory clinical trials in oncology. This assumption not only affects the analysis part but also the sample size ca…
Cancer phase I trial design using drug combinations when a fraction of dose limiting toxicities is attributable to one or more agents
Jose L. Jimenez, Mourad Tighiouart, Mauro Gasparini
Drug combination trials are increasingly common nowadays in clinical research. However, very few methods have been developed to consider toxicity attributions in the dose escalatio…