3 papers
q-bio.GN2021
Evolution of default genetic control mechanisms
William Bains, Enrico Borriello, Dirk Schulze-Makuch
We present a model of the evolution of control systems in a genome under environmental constraints. The model conceptually follows the Jacob and Monod model of gene control. Genes…
q-bio.MN2020
The basis of easy controllability in Boolean networks
Enrico Borriello, Bryan C. Daniels
Effective control of biological systems can often be achieved through the control of a surprisingly small number of distinct variables. We bring clarity to such results using the f…
physics.bio-ph2018
A unified formal framework for developmental andevolutionary change in gene regulatory network models
Enrico Borriello, Sara I. Walker, Manfred D. Laubichler
The two most fundamental processes describing change in biology, development and evolu-tion, occur over drastically different timescales, difficult to reconcile within a unified fr…