2 citations · 2 across the 6 of their papers we have counts for
6 papers
Monte Carlo Simulation and Dosimetric Analysis of Gold Nanoparticles (AuNPs) in Breast Tissue
Pedro Teles, Catarina Dias, João H. Belo +5
Precise radiation delivery is critical for effective radiotherapy, and gold nanoparticles (AuNPs) have emerged as promising tools to enhance local dose deposition while sparing the…
Using systemic modeling and Bayesian calibration to investigate the role of the tumor microenvironment on chemoresistance
Sabrina Schönfeld, Laura Scarabosio, Alican Ozkan +2
Using a novel modeling approach based on the so-called environmental stress level (ESL), we develop a mathematical model to describe systematically the collective influence of oxyg…
Environmental stress level to model tumor cell growth and survival
Sabrina Schönfeld, Alican Ozkan, Laura Scarabosio +2
Survival of living tumor cells underlies many influences such as nutrient saturation, oxygen level, drug concentrations or mechanical forces. Data-supported mathematical modeling c…
Mixture theory modeling for characterizing solute transport in breast tumor tissues
Sreyashi Chakraborty, Alican Ozkan, Marissa Nichole Rylander +2
Solute transport is modeled using mixture theory, applied to the nanoparticle accumulation and concentration decay in the tissue space for different vascular configurations. A comp…
In Vitro Vascularized Liver and Tumor Tissue Microenvironments on a Chip for Dynamic Determination of Nanoparticle Transport and Toxicity
Alican Ozkan, Neda Ghousifam, P. Jack Hoopes +1
This paper presents the development of a vascularized breast tumor and healthy or tumorigenic liver microenvironments-on-a-chip connected in series. This is the first description o…
In Vitro Vascularized Tumor Platform for Modeling Tumor-Vasculature Interactions of Inflammatory Breast Cancer
Manasa Gadde, Caleb Phillips, Neda Ghousifam +8
Inflammatory breast cancer (IBC), a rare form of breast cancer associated with increased angiogenesis and metastasis, is largely driven by tumor-stromal interactions with the vascu…