3 papers
q-bio.CB2023
Using systemic modeling and Bayesian calibration to investigate the role of the tumor microenvironment on chemoresistance
Sabrina Schönfeld, Laura Scarabosio, Alican Ozkan +2
Using a novel modeling approach based on the so-called environmental stress level (ESL), we develop a mathematical model to describe systematically the collective influence of oxyg…
q-bio.TO2018
Mixture theory modeling for characterizing solute transport in breast tumor tissues
Sreyashi Chakraborty, Alican Ozkan, Marissa Nichole Rylander +2
Solute transport is modeled using mixture theory, applied to the nanoparticle accumulation and concentration decay in the tissue space for different vascular configurations. A comp…
q-bio.TO2018
In Vitro Vascularized Liver and Tumor Tissue Microenvironments on a Chip for Dynamic Determination of Nanoparticle Transport and Toxicity
Alican Ozkan, Neda Ghousifam, P. Jack Hoopes +1
This paper presents the development of a vascularized breast tumor and healthy or tumorigenic liver microenvironments-on-a-chip connected in series. This is the first description o…