4 papers
A Biologically Motivated Asymmetric Exclusion Process: interplay of congestion in RNA polymerase traffic and slippage of nascent transcript
Soumendu Ghosh, Annwesha Dutta, Shubhadeep Patra +3
We develope a theoretical framework, based on exclusion process, that is motivated by a biological phenomenon called transcript slippage (TS). In this model a discrete lattice repr…
A biologically inspired two-species exclusion model: effects of RNA polymerase motor traffic on simultaneous DNA replication
Soumendu Ghosh, Bhavya Mishra, Shubhadeep Patra +2
We introduce a two-species exclusion model to describe the key features of the conflict between the RNA polymerase (RNAP) motor traffic, engaged in the transcription of a segment o…
First Passage Time in Computation by Tape-Copying Turing Machines: Slippage of Nascent Tape
Soumendu Ghosh, Shubhadeep Patra, Debashish Chowdhury
Transcription of the genetic message encoded chemically in the sequence of the DNA template is carried out by a molecular machine called RNA polymerase (RNAP). Backward or forward…
Molecular force spectroscopy of kinetochore-microtubule attachment {\it in silico}: Mechanical signatures of an unusual catch bond and collective effects
Dipanwita Ghanti, Shubhadeep Patra, Debashish Chowdhury
Measurement of the life time of attachments formed by a single microtubule (MT) with a single kinetochore (kt) {\it in-vitro} under force-clamp conditions had earlier revealed a ca…