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physics.bio-ph2026
An information-theoretic perspective on feed-forward loop abundances in transcriptional networks
Mintu Nandi, Sudip Chattopadhyay, Suman K Banik
In the transcriptional networks of \textit{Escherichia coli} and \textit{Saccharomyces cerevisiae}, the eight feed-forward loop (FFL) motifs occur at markedly different frequencies…
physics.bio-ph2026
Feedback-mediated circulation and persistence of stochastic fluctuations in gene regulatory circuits
Nashita Rahman, Mintu Nandi, Sudip Chattopadhyay +1
Feedback plays a significant role in biochemical networks that govern a multitude of cellular functions, including development, adaptation, and homeostasis. Yet, how feedback topol…
physics.bio-ph2026
Decoding cell signaling via optimal transport and information theory
Mintu Nandi, Sosuke Ito
Cellular signal processing performs reliably despite molecular noise. Mutual information (MI) is widely used to quantify signaling fidelity, capturing how well outputs discriminate…