2 papers
stat.ME2018
Joint modelling of progression-free and overall survival and computation of correlation measures
Matthias Meller, Jan Beyersmann, Kaspar Rufibach
In this paper, we derive the joint distribution of progression-free and overall survival as a function of transition probabilities in a multistate model. No assumptions on copulae…
stat.AP2018
A multistate model for early decision making in oncology
Ulrich Beyer, David Dejardin, Matthias Meller +2
The development of oncology drugs progresses through multiple phases, where after each phase a decision is made about whether to move a molecule forward. Early phase efficacy decis…