2 papers
stat.AP2018
Recent advances in methodology for clinical trials in small populations: the InSPiRe project
T. Friede, M. Posch, S. Zohar +19
Where there are a limited number of patients, such as in a rare disease, clinical trials in these small populations present several challenges, including statistical issues. This l…
stat.AP2018
Meta-analysis of few studies involving rare events
Burak Kürsad Günhan, Christian Röver, Tim Friede
Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number o…