2 papers
stat.ME2019
Efficient and flexible simulation-based sample size determination for clinical trials with multiple design parameters
Duncan T. Wilson, Rebecca E. A. Walwyn, Richard Hooper +2
Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, ho…
stat.ME2019
Bayesian design and analysis of external pilot trials for complex interventions
Duncan T. Wilson, James M. S. Wason, Julia Brown +2
External pilot trials of complex interventions are used to help determine if and how a confirmatory trial should be undertaken, providing estimates of parameters such as recruitmen…