activity
20092025
most citedSlow protein fluctuations explain the emergence of growth phenotypes and persistence in clonal bacterial populations

36 citations · 49 across the 5 of their papers we have counts for

collaborators

6 papers

quant-ph2025

The Effect of Permanent Dipoles on Dark States in Molecular Dimers

Matthew Freed, Dominic M. Rouse, Andrea Rocco +3

Many organic molecules possess large permanent dipole moments that differ depending on the electronic state. These permanent dipoles influence both intermolecular coupling and inte…

q-bio.MN2022★ 2 cited

Noise-induced transitions in gene circuits: a perturbative approach for slow noise

Gerardo Aquino, Andrea Rocco

We consider a generic class of gene circuits affected by nonlinear extrinsic noise. To address this nonlinearity we introduce a general perturbative methodology based on assuming t…

math.DS2021

Novel Generic Models for Differentiating Stem Cells Reveal Oscillatory Mechanisms

Saeed Farjami, Karen Camargo Sosa, Jonathan H. P. Dawes +2

Understanding cell fate selection remains a central challenge in developmental biology. We present a class of simple yet biologically-motivated mathematical models for cell differe…

physics.bio-ph2019

Bimodality in gene expression without feedback: From Gaussian white noise to log-normal coloured noise

Gerardo Aquino, Andrea Rocco

Extrinsic noise-induced transitions to bimodal dynamics have been largely investigated in a variety of chemical, physical, and biological systems. In the standard approach in physi…

q-bio.SC2013★ 36 cited

Slow protein fluctuations explain the emergence of growth phenotypes and persistence in clonal bacterial populations

Andrea Rocco, Andrzej M. Kierzek, Johnjoe McFadden

One of the most challenging problems in microbiology is to understand how a small fraction of microbes that resists killing by antibiotics can emerge in a population of genetically…

q-bio.SC2009★ 11 cited

Stochastic Control of Metabolic Pathways

Andrea Rocco

We study the effect of extrinsic noise in metabolic networks. We introduce external random fluctuations at the kinetic level, and show how these lead to a stochastic generalization…