5 papers · 1 filter
Few-Shot Bioactivity Prediction with Meta-Learning under Assay Heterogeneity
Michal Kmicikiewicz, Tommy Rochussen, Vincent Fortuin +1
Accurate bioactivity prediction is a central challenge in early-stage drug discovery, as individual assays often contain too few measurements to train reliable models independently…
ProSpero: Active Learning for Robust Protein Design Beyond Wild-Type Neighborhoods
Michal Kmicikiewicz, Vincent Fortuin, Ewa Szczurek
Designing protein sequences of both high fitness and novelty is a challenging task in data-efficient protein engineering. Exploration beyond wild-type neighborhoods often leads to…
Can Transformers Learn Full Bayesian Inference in Context?
Arik Reuter, Tim G. J. Rudner, Vincent Fortuin +1
Transformers have emerged as the dominant architecture in the field of deep learning, with a broad range of applications and remarkable in-context learning (ICL) capabilities. Whil…
OneProt: Towards Multi-Modal Protein Foundation Models
Klemens Flöge, Srisruthi Udayakumar, Johanna Sommer +8
Recent advances in Artificial Intelligence have enabled multi-modal systems to model and translate diverse information spaces. Extending beyond text and vision, we introduce OnePro…
Mixture-of-Experts Variational Autoencoder for Clustering and Generating from Similarity-Based Representations on Single Cell Data
Andreas Kopf, Vincent Fortuin, Vignesh Ram Somnath +1
Clustering high-dimensional data, such as images or biological measurements, is a long-standingproblem and has been studied extensively. Recently, Deep Clustering has gained popula…