activity
20162025
most citedRelating cell shape and mechanical stress in a spatially disordered epithelium using a vertex-based model

66 citations · 122 across the 6 of their papers we have counts for

collaborators

6 papers

physics.bio-ph2025

Modelling bulk mechanical effects in a planar cellular monolayer

Natasha Cowley, Sarah Woolner, Oliver E. Jensen

We use a three-dimensional formulation of the cell vertex model to describe the mechanical properties of a confluent planar monolayer of prismatic cells. Treating cell height as a…

physics.bio-ph2024★ 4 cited

Spectral approaches to stress relaxation in epithelial monolayers

Natasha Cowley, Christopher K. Revell, Emma Johns +2

We investigate the viscoelastic relaxation to equilibrium of a disordered planar epithelium described using the cell vertex model. In its standard form, the model is formulated as…

q-bio.SC2024

Relaxation and noise-driven oscillations in a model of mitotic spindle dynamics

Dionn Hargreaves, Sarah Woolner, Oliver E. Jensen

During cell division, the mitotic spindle moves dynamically through the cell to position the chromosomes and determine the ultimate spatial position of the two daughter cells. Thes…

physics.bio-ph2019★ 11 cited

Force networks, torque balance and Airy stress in the planar vertex model of a confluent epithelium

Oliver E. Jensen, Emma Johns, Sarah Woolner

The vertex model is a popular framework for modelling tightly packed biological cells, such as confluent epithelia. Cells are described by convex polygons tiling the plane and thei…

q-bio.CB2017★ 41 cited

Mechanical characterization of disordered and anisotropic cellular monolayers

Alexander Nestor-Bergmann, Emma Johns, Sarah Woolner +1

We consider a cellular monolayer, described using a vertex-based model, for which cells form a spatially disordered array of convex polygons that tile the plane. Equilibrium cell c…

q-bio.CB2016★ 66 cited

Relating cell shape and mechanical stress in a spatially disordered epithelium using a vertex-based model

Alexander Nestor-Bergmann, Georgina Goddard, Sarah Woolner +1

Using a popular vertex-based model to describe a spatially disordered planar epithelial monolayer, we examine the relationship between cell shape and mechanical stress at the cell…