7 citations · 11 across the 8 of their papers we have counts for
8 papers · 1 filter
Mechanistic insights into the spatial organization of RNA polymerase proteins and the chromosome in E. coli cells
Debarshi Mitra, Jens-Uwe Sommer
Along the bacterial chromosome, regions called rrn operons contain genes that are transcribed into ribosomal RNA. These operons are among the most transcriptionally active sites in…
Entropic alignment of topologically modified ring polymers in cylindrical confinement
Sanjay Bhandarkar, Debarshi Mitra, Jürgen Horbach +1
Under high cylindrical confinement, segments of ring polymers can be localized along the long axis of the cylinder by introducing internal loops within the ring polymer. The emerge…
Entropic organization of topologically modified ring polymers in spherical confinement
Kingkini Roychoudhury, Shreerang Pande, Indrakanty S. Shashank +2
It has been shown that under high cylindrical confinement, two ring polymers with excluded volume interactions between monomers, segregate to two halves of the cylinder to maximize…
Emergent helicity in free-standing semiflexible, charged polymers
Debarshi Mitra, Apratim Chatterji
Helical motifs are ubiquitious in macromolecular systems. The mechanism of spontaneous emergence of helicity is unknown, especially in cases where torsional interactions are absent…
Topology mediated organization of E.coli chromosome in fast growth conditions
Shreerang Pande, Debarshi Mitra, Apratim Chatterji
Recent experiments have been able to visualise chromosome organization in fast-growing E.coli cells. However, the mechanism underlying the spatio-temporal organization remains poor…
The role of polymer architecture in the entropy driven segregation and spatial organization of bacterial chromosomes
Debarshi Mitra, Shreerang Pande, Apratim Chatterji
Entropic repulsion between DNA ring polymers under confinement is the key mechanism governing the spatial segregation of bacterial chromosomes, although it remains incompletely und…
DNA-polymer architecture orchestrates the segregation and spatio-temporal organization of E. coli chromosomes during replication in slow growth
Debarshi Mitra, Shreerang Pande, Apratim Chatterji
The mechanism and driving forces of chromosome segregation in the bacterial cell cycle of E. coli is one of the least understood events in its life cycle. Using principles of entro…
Transient helix formation in semiflexible polymers without confinement effects
Debarshi Mitra, Apratim Chatterji
Generic interactions e.g. the Coulomb or other long ranged radially symmetric repulsive interactions between monomers of bead-spring model of a semi-flexible polymer induce instabi…