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stat.ME2023
Bayesian Optimization for Personalized Dose-Finding Trials with Combination Therapies
James Willard, Shirin Golchi, Erica E. M. Moodie +2
Identification of optimal dose combinations in early phase dose-finding trials is challenging, due to the trade-off between precisely estimating the many parameters required to fle…
stat.ME2023
Estimating the Sampling Distribution of Posterior Decision Summaries in Bayesian Clinical Trials
Shirin Golchi, James Willard
Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in B…