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q-bio.PE2025
Synergistic interplay of morphology and metabolic activity rule response to CAR-T cells in B-cell lymphomas
Yifan Chen, Soukaina Sabir, Christina Kuttler +13
Cellular immunotherapies are one of the mainstream cancer treatments unveiling the power of the patient's immune system to fight tumors. CAR T-cell therapy, based on genetically en…
q-bio.TO2025
Geometric immunosuppression in CAR-T cell treatment: Insights from mathematical modeling
Silvia Bordel-Vozmediano, Soukaina Sabir, Lucía Benito-Barca +2
Chimeric antigen receptor T (CAR-T) cell therapy has emerged as a promising treatment for hematological malignancies, offering a targeted approach to cancer treatment. Understandin…