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q-bio.QM2022
Topological Data Analysis of Spatial Patterning in Heterogeneous Cell Populations: Clustering and Sorting with Varying Cell-Cell Adhesion
Dhananjay Bhaskar, William Y. Zhang, Alexandria Volkening +2
Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength…
q-bio.QM2020
Topological Data Analysis of Collective and Individual Epithelial Cells using Persistent Homology of Loops
Dhananjay Bhaskar, William Y. Zhang, Ian Y. Wong
Interacting, self-propelled particles such as epithelial cells can dynamically self-organize into complex multicellular patterns, which are challenging to classify without a priori…