2 papers
physics.bio-ph2022
Systematic conformation-to-phenotype mapping via limited deep-sequencing of proteins
Eugene Serebryany, Victor Y. Zhao, Kibum Park +4
Non-native conformations drive protein misfolding diseases, complicate bioengineering efforts, and fuel molecular evolution. No current experimental technique is well-suited for el…
q-bio.BM2020
Effect of protein structure on evolution of cotranslational folding
Victor Zhao, William M. Jacobs, Eugene I. Shakhnovich
Cotranslational folding depends on the folding speed and stability of the nascent protein. It remains difficult, however, to predict which proteins cotranslationally fold. Here, we…