activity
20182026
most citedSynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining

641 citations · 823 across the 21 of their papers we have counts for

collaborators

22 papers

eess.IV2026

Uncertainty-Aware Cortical Surface Reconstruction and Spherical Registration for Heterogeneous Brain MRI

Jesper Duemose Nielsen, Karthik Gopinath, Andrew Hoopes +4

Surface-based cortical analysis is useful in many applications as it is a natural way to model the highly folded structure of the cerebral cortex, allowing quantities such as curva…

cs.CV2025

Deep generative priors for 3D brain analysis

Ana Lawry Aguila, Dina Zemlyanker, You Cheng +6

Diffusion models have recently emerged as powerful generative models in medical imaging. However, it remains a major challenge to combine these data-driven models with domain knowl…

cs.CV2025

A Modality-agnostic Multi-task Foundation Model for Human Brain Imaging

Peirong Liu, Oula Puonti, Xiaoling Hu +5

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated mod…

eess.IV2025

Conditional diffusion models for guided anomaly detection in brain images using fluid-driven anomaly randomization

Ana Lawry Aguila, Peirong Liu, Oula Puonti +1

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scena…

eess.IV2025

End-to-end Cortical Surface Reconstruction from Clinical Magnetic Resonance Images

Jesper Duemose Nielsen, Karthik Gopinath, Andrew Hoopes +7

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, mo…

cs.CV2025★ 1 cited

From Low Field to High Value: Robust Cortical Mapping from Low-Field MRI

Karthik Gopinath, Annabel Sorby-Adams, Jonathan W. Ramirez +12

Three-dimensional reconstruction of cortical surfaces from MRI for morphometric analysis is fundamental for understanding brain structure. While high-field MRI (HF-MRI) is standard…

cs.CV2025

Learning to Upscale 3D Segmentations in Neuroimaging

Xiaoling Hu, Peirong Liu, Dina Zemlyanker +3

Obtaining high-resolution (HR) segmentations from coarse annotations is a pervasive challenge in computer vision. Applications include inferring pixel-level segmentations from toke…

eess.IV2025

Reference-Free 3D Reconstruction of Brain Dissection Slabs via Learned Atlas Coordinates

Lin Tian, Jonathan Williams-Ramirez, Dina Zemlyanker +14

Correlation of neuropathology with MRI has the potential to transfer microscopic signatures of pathology to in vivo scans. There is increasing interest in building these correlatio…

cs.CV2024

Learn2Synth: Learning Optimal Data Synthesis Using Hypergradients for Brain Image Segmentation

Xiaoling Hu, Xiangrui Zeng, Oula Puonti +3

Domain randomization through synthesis is a powerful strategy to train networks that are unbiased with respect to the domain of the input images. Randomization allows networks to s…

cs.CV2024

Hierarchical Uncertainty Estimation for Learning-based Registration in Neuroimaging

Xiaoling Hu, Karthik Gopinath, Peirong Liu +4

Over recent years, deep learning based image registration has achieved impressive accuracy in many domains, including medical imaging and, specifically, human neuroimaging with mag…

eess.IV2024★ 2 cited

Recon-all-clinical: Cortical surface reconstruction and analysis of heterogeneous clinical brain MRI

Karthik Gopinath, Douglas N. Greve, Colin Magdamo +4

Surface-based analysis of the cerebral cortex is ubiquitous in human neuroimaging with MRI. It is crucial for cortical registration, parcellation, and thickness estimation. Traditi…

eess.IV2024

High-resolution segmentations of the hypothalamus and its subregions for training of segmentation models

Livia Rodrigues, Martina Bocchetta, Oula Puonti +6

Segmentation of brain structures on magnetic resonance imaging (MRI) is a highly relevant neuroimaging topic, as it is a prerequisite for different analyses such as volumetry or sh…

cs.CV2024

Registration by Regression (RbR): a framework for interpretable and flexible atlas registration

Karthik Gopinath, Xiaoling Hu, Malte Hoffmann +2

In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learn…

eess.IV2024

P-Count: Persistence-based Counting of White Matter Hyperintensities in Brain MRI

Xiaoling Hu, Annabel Sorby-Adams, Frederik Barkhof +3

White matter hyperintensities (WMH) are a hallmark of cerebrovascular disease and multiple sclerosis. Automated WMH segmentation methods enable quantitative analysis via estimation…

eess.IV2024

PEPSI: Pathology-Enhanced Pulse-Sequence-Invariant Representations for Brain MRI

Peirong Liu, Oula Puonti, Annabel Sorby-Adams +2

Remarkable progress has been made by data-driven machine-learning methods in the analysis of MRI scans. However, most existing MRI analysis approaches are crafted for specific MR p…

eess.IV2024★ 2 cited

H-SynEx: Using synthetic images and ultra-high resolution ex vivo MRI for hypothalamus subregion segmentation

Livia Rodrigues, Martina Bocchetta, Oula Puonti +6

The hypothalamus is a small structure located in the center of the brain and is involved in significant functions such as sleeping, temperature, and appetite control. Various neuro…

eess.IV2023★ 12 cited

Quantifying white matter hyperintensity and brain volumes in heterogeneous clinical and low-field portable MRI

Pablo Laso, Stefano Cerri, Annabel Sorby-Adams +21

Brain atrophy and white matter hyperintensity (WMH) are critical neuroimaging features for ascertaining brain injury in cerebrovascular disease and multiple sclerosis. Automated se…

cs.CV2023★ 1 cited

Brain-ID: Learning Contrast-agnostic Anatomical Representations for Brain Imaging

Peirong Liu, Oula Puonti, Xiaoling Hu +2

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated mod…

cs.CV2023

A Lightweight Generative Model for Interpretable Subject-level Prediction

Chiara Mauri, Stefano Cerri, Oula Puonti +2

Recent years have seen a growing interest in methods for predicting an unknown variable of interest, such as a subject's diagnosis, from medical images depicting its anatomical-fun…

eess.IV2021★ 641 cited

SynthSeg: Segmentation of brain MRI scans of any contrast and resolution without retraining

Benjamin Billot, Douglas N. Greve, Oula Puonti +5

Despite advances in data augmentation and transfer learning, convolutional neural networks (CNNs) difficultly generalise to unseen domains. When segmenting brain scans, CNNs are hi…

eess.IV2020★ 164 cited

A Contrast-Adaptive Method for Simultaneous Whole-Brain and Lesion Segmentation in Multiple Sclerosis

Stefano Cerri, Oula Puonti, Dominik S. Meier +4

Here we present a method for the simultaneous segmentation of white matter lesions and normal-appearing neuroanatomical structures from multi-contrast brain MRI scans of multiple s…

cs.CV2018

A Modality-Adaptive Method for Segmenting Brain Tumors and Organs-at-Risk in Radiation Therapy Planning

Mikael Agn, Per Munck af Rosenschöld, Oula Puonti +7

In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method comb…