457 citations · 470 across the 5 of their papers we have counts for
5 papers
Towards a Unified Framework for Determining Conformational Ensembles of Disordered Proteins
Hamidreza Ghafouri, Pavel Kadeřávek, Ana M Melo +23
Disordered proteins play essential roles in myriad cellular processes, yet their structural characterization remains a major challenge due to their dynamic and heterogeneous nature…
Best practices for the manual curation of Intrinsically Disordered Proteins in DisProt
Federica Quaglia, Anastasia Chasapi, Maria Victoria Nugnes +4
The DisProt database is a significant resource containing manually curated data on experimentally validated intrinsically disordered proteins (IDPs) and regions (IDRs) from the lit…
CAFA-evaluator: A Python Tool for Benchmarking Ontological Classification Methods
Damiano Piovesan, Davide Zago, Parnal Joshi +8
We present CAFA-evaluator, a powerful Python program designed to evaluate the performance of prediction methods on targets with hierarchical concept dependencies. It generalizes mu…
DOME: Recommendations for supervised machine learning validation in biology
Ian Walsh, Dmytro Fishman, Dario Garcia-Gasulla +6
Modern biology frequently relies on machine learning to provide predictions and improve decision processes. There have been recent calls for more scrutiny on machine learning perfo…
An expanded evaluation of protein function prediction methods shows an improvement in accuracy
Yuxiang Jiang, Tal Ronnen Oron, Wyatt T Clark +144
Background: The increasing volume and variety of genotypic and phenotypic data is a major defining characteristic of modern biomedical sciences. At the same time, the limitations i…