3 papers
q-bio.CB2026
Spatial dynamic modelling to understand how dendritic cell clustering affects T cell activation
Domenic P. J. Germano, Federico Frascoli, Robyn P. Araujo +2
The coordination of the immune system and its components is essential for the body to maintain a healthy status. Recent clinical studies show that breast cancer patients with high…
q-bio.PE2026
Multiscale Modelling of Birth-Death Processes
Tom Kimpson, Domenic P. J. Germano, Jennifer A. Flegg +1
Many biological systems exhibit multiscale dynamics, where some species occur in high copy numbers while others remain rare. This heterogeneity necessitates hybrid modelling approa…
q-bio.TO2020
A mathematical model of cell fate selection on a dynamic tissue
Domenic P. J. Germano, James M. Osborne
Multicellular tissues are the building blocks of many biological systems and organs. These tissues are not static, but dynamically change over time. Even if the overall structure r…