1 citations · 1 across the 4 of their papers we have counts for
6 papers
T-cell repertoire response in individuals with post-acute sequelae of COVID-19
Zachary Montague, Rhea M Grover, Andrew Baumgartner +3
T-cells are central to SARS-CoV-2 clearance and immunological memory, yet their contribution to the persistence of post-acute sequelae of COVID-19 (PASC) remains poorly understood.…
Design principles of the cytotoxic CD8+ T-cell response
Obinna A. Ukogu, Zachary Montague, Grégoire Altan-Bonnet +1
Cytotoxic T lymphocytes eliminate infected or malignant cells, safeguarding surrounding tissues. Although experimental and systems-immunology studies have cataloged many molecular…
Adaptive efficiency of information processing in immune-pathogen co-evolution
Quinn N Bellamy, Zachary Montague, Luca Peliti +1
Organisms have evolved immune systems that can counter pathogenic threats. The adaptive immune system in vertebrates consists of a diverse repertoire of immune receptors that can d…
Learning the shape of protein micro-environments with a holographic convolutional neural network
Michael N. Pun, Andrew Ivanov, Quinn Bellamy +5
Proteins play a central role in biology from immune recognition to brain activity. While major advances in machine learning have improved our ability to predict protein structure f…
Dynamics of B-cell repertoires and emergence of cross-reactive responses in COVID-19 patients with different disease severity
Zachary Montague, Huibin Lv, Jakub Otwinowski +12
COVID-19 patients show varying severity of the disease ranging from asymptomatic to requiring intensive care. Although a number of SARS-CoV-2 specific monoclonal antibodies have be…
Telescoping jet substructure
Yang-Ting Chien, Alex Emerman, Shih-Chieh Hsu +2
We introduce a novel jet substructure method which exploits the variation of observables with respect to a sampling of phase-space boundaries quantified by the variability. We appl…