125 citations · 226 across the 9 of their papers we have counts for
3 papers · 1 filter
Protriever: End-to-End Differentiable Protein Homology Search for Fitness Prediction
Ruben Weitzman, Peter Mørch Groth, Lood Van Niekerk +4
Retrieving homologous protein sequences is essential for a broad range of protein modeling tasks such as fitness prediction, protein design, structure modeling, and protein-protein…
DiscoBAX: Discovery of Optimal Intervention Sets in Genomic Experiment Design
Clare Lyle, Arash Mehrjou, Pascal Notin +4
The discovery of therapeutics to treat genetically-driven pathologies relies on identifying genes involved in the underlying disease mechanisms. Existing approaches search over the…
RITA: a Study on Scaling Up Generative Protein Sequence Models
Daniel Hesslow, Niccoló Zanichelli, Pascal Notin +2
In this work we introduce RITA: a suite of autoregressive generative models for protein sequences, with up to 1.2 billion parameters, trained on over 280 million protein sequences…