activity
20202023
most citedReal-time observation of ligand-induced allosteric transitions in a PDZ domain

76 citations · 105 across the 4 of their papers we have counts for

collaborators

5 papers

physics.bio-ph2023★ 1 cited

Transient 2D IR spectroscopy and multiscale simulations reveal vibrational couplings in the Cyanobacteriochrome Slr1393-g3

David Buhrke, Yigal Lahav, Aditya Rao +3

Cyanobacteriochromes are bi-stable photoreceptor proteins with desirable photochemical properties for biotechnological applications such as optogenetics or fluorescence microscopy.…

physics.bio-ph2021

The Speed of Allosteric Signaling Within a Single-Domain Protein

Olga Bozovic, Jeannette Ruf, Claudio Zanobini +4

While much is known about different allosteric regulation mechanisms, the nature of the "allosteric signal", and the timescale on which it propagates, remains elusive. The PDZ3 dom…

physics.bio-ph2021

Sequence of Events During Peptide Unbinding from RNase S: A Complete Experimental Description

Brankica Jankovic, Jeannette Ruf, Claudio Zanobini +3

The photo-triggered unbinding of the intrinsically disordered S-peptide from the RNase S complex is studied with the help of transient IR spectroscopy, covering a wide range of tim…

physics.bio-ph2020★ 28 cited

Nanosecond protein dynamics in a red/green Cyanobacteriochrome revealed by transient IR spectroscopy

David Buhrke, Kerstin T. Oppelt, Philipp J. Heckmeier +2

Over the last decades, photoreceptive proteins were extensively studied with biophysical methods to gain a fundamental understanding of their working mechanisms and further guide t…

physics.bio-ph2020★ 76 cited

Real-time observation of ligand-induced allosteric transitions in a PDZ domain

Olga Bozovic, Claudio Zanobini, Adnan Gulzar +6

While allostery is of paramount importance for protein regulation, the underlying dynamical process of ligand (un)binding at one site, resulting time evolution of the protein struc…