2 papers
q-bio.PE2020
City-Scale Agent-Based Simulators for the Study of Non-Pharmaceutical Interventions in the Context of the COVID-19 Epidemic
Shubhada Agrawal, Siddharth Bhandari, Anirban Bhattacharjee +14
We highlight the usefulness of city-scale agent-based simulators in studying various non-pharmaceutical interventions to manage an evolving pandemic. We ground our studies in the c…
q-bio.PE2020
The weakest link bridging germinal center B cells and follicular dendritic cells limits antibody affinity maturation
Rajat Desikan, Rustom Antia, Narendra M. Dixit
The affinity of antibodies (Abs) produced in vivo for their target antigens (Ags) is typically well below the maximum affinity possible. Nearly 25 years ago, Foote and Eisen explai…