14 citations · 17 across the 3 of their papers we have counts for
3 papers
Adjusting for time-varying treatment switches in randomized clinical trials: the danger of extrapolation and how to avoid it
Hege Michiels, An Vandebosch, Stijn Vansteelandt
When choosing estimands and estimators in randomized clinical trials, caution is warranted as intercurrent events, such as - due to patients who switch treatment after disease prog…
Estimands and their Estimators for Clinical Trials Impacted by the COVID-19 Pandemic: A Report from the NISS Ingram Olkin Forum Series on Unplanned Clinical Trial Disruptions
Kelly Van Lancker, Sergey Tarima, Jonathan Bartlett +8
The COVID-19 pandemic continues to affect the conduct of clinical trials globally. Complications may arise from pandemic-related operational challenges such as site closures, trave…
A novel estimand to adjust for rescue treatment in clinical trials
Hege Michiels, Cristina Sotto, An Vandebosch +1
The interpretation of randomised clinical trial results is often complicated by intercurrent events. For instance, rescue medication is sometimes given to patients in response to w…