4 papers
Optimal vaccine roll-out strategies with respect to social distancing measures for SARS-CoV-2 pandemic
Konstantinos Spiliotis, Constantinos Chr. Koutsoumaris, Andreas Reppas +2
Non-pharmacological interventions (NPIs), and in particular social distancing, in conjunction with the advent of effective vaccines at the end of 2020, aspired for the development…
A biophysical network model reveals the link between deficient inhibitory cognitive control and major neurotransmitter and neural connectivity hypotheses in schizophrenia
Konstantinos Spiliotis, Giannis Kahramanoglou, Jens Starke +2
We address a biophysical network dynamical model to study how the modulation of dopamine (DA) activity and related N-methyl-d-aspartate (NMDA) glutamate receptor activity as well a…
Deep brain stimulation for movement disorder treatment: Exploring frequency-dependent efficacy in a computational network model
Konstantinos Spiliotis, Jens Starke, Denise Franz +2
A large scale computational model of the basal ganglia (BG) network is proposed to describes movement disorder including deep brain stimulation (DBS). The model of this complex net…
Coarse-scale PDEs from fine-scale observations via machine learning
Seungjoon Lee, Mahdi Kooshkbaghi, Konstantinos Spiliotis +2
Complex spatiotemporal dynamics of physicochemical processes are often modeled at a microscopic level (through e.g. atomistic, agent-based or lattice models) based on first princip…