3 citations · 3 across the 4 of their papers we have counts for
4 papers
Causal Discovery of Radiation Response Mechanisms in Human Cells
Ashka Shah, Rick Stevens
Next-generation sequencing technologies, including RNA-sequencing, provide genome-wide measurements of gene expression and enable broad explorations of biomarkers and mechanisms un…
Causal Discovery and Optimal Experimental Design for Genome-Scale Biological Network Recovery
Ashka Shah, Arvind Ramanathan, Valerie Hayot-Sasson +1
Causal discovery of genome-scale networks is important for identifying pathways from genes to observable traits - e.g. differences in cell function, disease, drug resistance and ot…
Scaffold-Induced Molecular Graph (SIMG): Effective Graph Sampling Methods for High-Throughput Computational Drug Discovery
Austin Clyde, Ashka Shah, Max Zvyagin +2
Scaffold based drug discovery (SBDD) is a technique for drug discovery which pins chemical scaffolds as the framework of design. Scaffolds, or molecular frameworks, organize the de…
IMPECCABLE: Integrated Modeling PipelinE for COVID Cure by Assessing Better LEads
Aymen Al Saadi, Dario Alfe, Yadu Babuji +33
The drug discovery process currently employed in the pharmaceutical industry typically requires about 10 years and $2-3 billion to deliver one new drug. This is both too expensive…