4 papers
Transition paths in Potts-like energy landscapes: general properties and application to protein sequence models
Eugenio Mauri, Simona Cocco, Rémi Monasson
We study transition paths in energy landscapes over multi-categorical Potts configurations using the mean-field approach introduced by Mauri et al., {\em Phys Rev Lett 130, 158402…
Mutational paths with sequence-based models of proteins: from sampling to mean-field characterisation
Eugenio Mauri, Simona Cocco, Rémi Monasson
Identifying and characterizing mutational paths is an important issue in evolutionary biology and in bioengineering. We here introduce a generic description of mutational paths in…
Gaussian Closure Scheme in the Quasi-Linkage Equilibrium Regime of Evolving Genome Populations
Eugenio Mauri, Simona Cocco, Rémi Monasson
Describing the evolution of a population of genomes evolving in a complex fitness landscape is generally very hard. We here introduce an approximate Gaussian closure scheme to char…
Inferring epistasis from genomic data with comparable mutation and outcrossing rate
Hong-Li Zeng, Eugenio Mauri, Vito Dichio +3
We consider a population evolving due to mutation, selection and recombination, where selection includes single-locus terms (additive fitness) and two-loci terms (pairwise epistati…