2 papers
physics.bio-ph2020
Simulating topological domains in human chromosomes with a fitting-free model
C. A. Brackley, D. Michieletto, F. Mouvet +4
We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinforma…
physics.bio-ph2016
Ephemeral protein binding to DNA shapes stable nuclear bodies and chromatin domains
C. A. Brackley, B. Liebchen, D. Michieletto +3
Fluorescence microscopy reveals that the contents of many (membrane-free) nuclear "bodies" exchange rapidly with the soluble pool whilst the underlying structure persists; such obs…