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stat.ME2021
A hierarchical prior for generalized linear models based on predictions for the mean response
Ethan M. Alt, Matthew A. Psioda, Joseph G. Ibrahim
There has been increased interest in using prior information in statistical analyses. For example, in rare diseases, it can be difficult to establish treatment efficacy based solel…
stat.ME2021
The scale transformed power prior for use with historical data from a different outcome model
Brady Nifong, Matthew A. Psioda, Joseph G. Ibrahim
We develop the scale transformed power prior for settings where historical and current data involve different data types, such as binary and continuous data, respectively. This sit…
stat.ME2020
Bayesian Multivariate Probability of Success Using Historical Data with Strict Control of Family-wise Error Rate
Ethan M. Alt, Matthew A. Psioda, Joseph G. Ibrahim
Given the cost and duration of phase III and phase IV clinical trials, the development of statistical methods for go/no-go decisions is vital. In this paper, we introduce a Bayesia…