9 citations · 9 across the 4 of their papers we have counts for
5 papers
Advancing glaucoma research with multiphysics continuum mechanics modelling: Opportunities and open challenges
Daniel Sebastia-Saez, Jinyuan Luo, Mengqi Qin +2
This review examines the emerging role of mechanistic mathematical models based on continuum mechanics to address current challenges in glaucoma research. At present, the advent of…
Comparative CFD modelling of the interplay between aqueous humour hydrodynamics and drug and nanocarrier transport for glaucoma drug delivery via intracameral injection, drug-eluting implants and contact lenses
Nazifa Begum, Robert Dinita, Naman Patel +4
Glaucoma is the leading cause of irreversible blindness worldwide and often requires long-term administration of intraocular pressure-lowering agents. The effectiveness of ocular d…
In silico study on the contribution of the follicular route to dermal permeability of small molecules
Daniel Sebastia-Saez, Guoping Lian, Tao Chen
Purpose. This study investigates in silico the contribution of the hair follicle to the overall dermal permeability of small molecules, as published experimental work provides inco…
Numerical analysis of the strain distribution in skin domes formed upon the application of hypobaric pressure
Daniel Sebastia-Saez, Faiza Benaouda, Charlie Lim +4
Suction cups are widely used in applications such as in measurement of mechanical properties of skin in vivo, in drug delivery devices or in acupuncture treatment. Understanding th…
New trends in mechanistic transdermal drug delivery modelling: Towards an accurate description of skin microstructure
Daniel Sebastia-Saez, Adam Burbidge, Jan Engmann +1
Interest for in silico modelling of the absorption of xenobiotics into the skin has been growing in the last years, owing to their lower cost compared to experimental alternatives,…