activity
20202025
most citedZero-Shot 3D Drug Design by Sketching and Generating

9 citations · 13 across the 6 of their papers we have counts for

collaborators

6 papers

q-bio.BM2025

AMix-1: A Pathway to Test-Time Scalable Protein Foundation Model

Changze Lv, Jiang Zhou, Siyu Long +22

We introduce AMix-1, a powerful protein foundation model built on Bayesian Flow Networks and empowered by a systematic training methodology, encompassing pretraining scaling laws,…

q-bio.BM2025★ 1 cited

Steering Protein Family Design through Profile Bayesian Flow

Jingjing Gong, Yu Pei, Siyu Long +7

Protein family design emerges as a promising alternative by combining the advantages of de novo protein design and mutation-based directed evolution.In this paper, we propose Profi…

q-bio.BM2024★ 2 cited

ESM All-Atom: Multi-scale Protein Language Model for Unified Molecular Modeling

Kangjie Zheng, Siyu Long, Tianyu Lu +6

Protein language models have demonstrated significant potential in the field of protein engineering. However, current protein language models primarily operate at the residue scale…

cs.CL2023

BED: Bi-Encoder-Decoder Model for Canonical Relation Extraction

Nantao Zheng, Siyu Long, Xinyu Dai

Canonical relation extraction aims to extract relational triples from sentences, where the triple elements (entity pairs and their relationship) are mapped to the knowledge base. R…

cs.CE2022★ 9 cited

Zero-Shot 3D Drug Design by Sketching and Generating

Siyu Long, Yi Zhou, Xinyu Dai +1

Drug design is a crucial step in the drug discovery cycle. Recently, various deep learning-based methods design drugs by generating novel molecules from scratch, avoiding traversin…

cs.CL2020★ 1 cited

Synonym Knowledge Enhanced Reader for Chinese Idiom Reading Comprehension

Siyu Long, Ran Wang, Kun Tao +2

Machine reading comprehension (MRC) is the task that asks a machine to answer questions based on a given context. For Chinese MRC, due to the non-literal and non-compositional sema…