6 papers
Activation in Vesicle-Mediated Signaling Shaped by Batch Arrival Statistics
Jan Hauke, Julian B. Voits, Ulrich S. Schwarz
Vesicle-mediated secretion of ions or molecules is a central mechanism of cellular communication, for example in processes such as neurotransmission or hormone release. These event…
Graph theoretic derivation of mutual linearity for transient probabilities and hitting time distributions in Markov networks
Julian B. Voits, Ulrich S. Schwarz
For irreducible, time-homogeneous Markov networks, mutual linearity has recently been established for both occupation probabilities and network currents in the stationary regime as…
Emergence of generic first-passage time distributions for large Markovian networks
Julian B. Voits, Ulrich S. Schwarz
First-passage times are often the most relevant aspect of a complex Markovian network because they signify when information processing has resulted in a definite decision. Previous…
Understanding the temperature response of biological systems: Part II -- Network-level mechanisms and emergent dynamics
Simen Jacobs, Julian B. Voits, Nikita Frolov +2
Building on the phenomenological and microscopic models reviewed in Part I, this second part focuses on network-level mechanisms that generate emergent temperature response curves.…
Understanding the temperature response of biological systems: Part I -- Phenomenological descriptions and microscopic models
Simen Jacobs, Julian Voits, Nikita Frolov +2
Virtually every biological rate depends on temperature, yet the resulting rate-temperature relationships often deviate strongly from simple Arrhenius behavior. In this first part o…
The generic temperature response of large biochemical networks
Julian B. Voits, Ulrich S. Schwarz
Biological systems are remarkably susceptible to relatively small temperature changes. The most obvious example is fever, when a modest rise in body temperature of only few Kelvin…