31 citations · 51 across the 7 of their papers we have counts for
8 papers
Multi-objective CFD optimization of an intermediate diffuser stage for PediaFlow pediatric ventricular assist device
Mansur Zhussupbekov, JingChun Wu, Greg W Burgreen +3
Background: Computational fluid dynamics (CFD) has become an essential design tool for ventricular assist devices (VADs), where the goal of maximizing performance often conflicts w…
Exploratory Simulation of Thrombosis in a Temporary LVAD Catheter Pump within a Virtual In-vivo Left Heart Environment
Greg W. Burgreen, Mansur Zhussupbekov, Rodrigo Méndez Rojano +1
Percutaneous catheter pumps are intraventricular temporary mechanical circulatory support (MCS) devices that are positioned across the aortic valve into the left ventricle (LV) and…
Automated CFD shape optimization of stator blades for the PediaFlow pediatric ventricular assist device
Mansur Zhussupbekov, Greg W Burgreen, Jeongho Kim +1
PediaFlow is a miniature mixed-flow ventricular assist device for neonates and toddlers. PediaFlow has a fully magnetically levitated rotor which improves biocompatibility, but the…
von Willebrand Factor unfolding mediates platelet deposition in a model of high-shear thrombosis
Mansur Zhussupbekov, Rodrigo Mendez Rojano, Wei-Tao Wu +1
Thrombosis under high-shear conditions is mediated by the mechanosensitive blood glycoprotein von Willebrand Factor (vWF). vWF unfolds in response to strong flow gradients and faci…
A continuum model for the unfolding of von Willebrand Factor
Mansur Zhussupbekov, Rodrigo Mendez Rojano, Wei-Tao Wu +2
von Willebrand Factor is a mechano-sensitive protein circulating in blood that mediates platelet adhesion to subendothelial collagen and platelet aggregation at high shear rates. I…
Uncertainty quantification of a thrombosis model considering the clotting assay PFA-100
Rodrigo Méndez Rojano, Mansur Zhussupbekov, James F. Antaki +1
Mathematical models of thrombosis are currently used to study clinical scenarios of pathological thrombus formation. Most of these models involve inherent uncertainties that must b…