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stat.ME2024
Nonparametric estimation of the total treatment effect with multiple outcomes in the presence of terminal events
Jessica Gronsbell, Zachary R. McCaw, Isabelle-Emmanuella Nogues +4
As standards of care advance, patients are living longer and once-fatal diseases are becoming manageable. Clinical trials increasingly focus on reducing disease burden, which can b…
stat.ME2023
Testing a Large Number of Composite Null Hypotheses Using Conditionally Symmetric Multidimensional Gaussian Mixtures in Genome-Wide Studies
Ryan Sun, Zachary McCaw, Xihong Lin
Causal mediation analysis, pleiotropy analysis, and replication analysis are three highly popular genetic study designs. Although these analyses address different scientific questi…