activity
20182020
most citedSurvival analysis for AdVerse events with VarYing follow-up times (SAVVY) -- estimation of adverse event risks

28 citations · 32 across the 3 of their papers we have counts for

collaborators

6 papers

stat.AP2020

Design aspects of COVID-19 treatment trials: Improving probability and time of favourable events

Jan Beyersmann, Tim Friede, Claudia Schmoor

As a reaction to the pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a multitude of clinical trials for the treatment of SARS-CoV-2 or the resulting c…

stat.AP2020★ 28 cited

Survival analysis for AdVerse events with VarYing follow-up times (SAVVY) -- estimation of adverse event risks

Regina Stegherr, Claudia Schmoor, Jan Beyersmann +12

The SAVVY project aims to improve the analyses of adverse event (AE) data in clinical trials through the use of survival techniques appropriately dealing with varying follow-up tim…

stat.AP2020★ 4 cited

Survival analysis for AdVerse events with VarYing follow-up times (SAVVY) -- comparison of adverse event risks in randomized controlled trials

Kaspar Rufibach, Regina Stegherr, Claudia Schmoor +12

Analyses of adverse events (AEs) are an important aspect of the evaluation of experimental therapies. The SAVVY (Survival analysis for AdVerse events with Varying follow-up times)…

stat.AP2020

Estimating and comparing adverse event probabilities in the presence of varying follow-up times and competing events

Regina Stegherr, Claudia Schmoor, Michael Lübbert +2

Safety analyses in terms of adverse events (AEs) are an important aspect of benefit-risk assessments of therapies. Compared to efficacy analyses AE analyses are often rather simpli…

stat.AP2019

Survival analysis for AdVerse events with VarYing follow-up times (SAVVY): Rationale and statistical concept of a meta-analytic study

Regina Stegherr, Jan Beyersmann, Valentine Jehl +4

The assessment of safety is an important aspect of the evaluation of new therapies in clinical trials, with analyses of adverse events being an essential part of this. Standard met…

stat.OT2018

On estimands and the analysis of adverse events in the presence of varying follow-up times within the benefit assessment of therapies

Steffen Unkel, Marjan Amiri, Norbert Benda +14

The analysis of adverse events (AEs) is a key component in the assessment of a drug's safety profile. Inappropriate analysis methods may result in misleading conclusions about a th…