3 papers
q-bio.QM2026
A Predictive Model for Synergistic Oncolytic Virotherapy: Unveiling the Ping-Pong Mechanism and Optimal Timing of Combined Vesicular Stomatitis and Vaccinia Viruses
Joseph Malinzi, Amina Eladdadi, Rachid Ouifki +3
We present a mathematical model that describes the synergistic mechanism of combined Vesicular Stomatitis Virus (VSV) and Vaccinia Virus (VV). The model captures the dynamic interp…
q-bio.TO2020
Prospect for application of mathematical models in combination cancer treatments
Joseph Malinzi, Kevin Bosire Basita, Sara Padidar +1
The long-term efficacy of targeted therapeutics for cancer treatment can be significantly limited by the type of therapy and development of drug resistance, inter alia. Experimenta…
math.OC2018
Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis
Joseph Malinzi, Rachid Ouifki, Amina Eladdadi +2
Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects. T…