5 citations · 6 across the 3 of their papers we have counts for
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stat.ME2022
Seamless Phase 2-3 Design: A Useful Strategy to Reduce the Sample Size for Dose Optimization
Liyun Jiang, Ying Yuan
The traditional more-is-better dose selection paradigm, developed based on cytotoxic chemotherapeutics, is often problematic When applied to the development of novel molecularly ta…
stat.ME2020★ 1 cited
Optimal Bayesian hierarchical model to accelerate the development of tissue-agnostic drugs and basket trials
Liyun Jiang, Lei Nie, Fangrong Yan +1
Tissue-agnostic trials enroll patients based on their genetic biomarkers, not tumor type, in an attempt to determine if a new drug can successfully treat disease conditions based o…
stat.ME2020★ 5 cited
Elastic Priors to Dynamically Borrow Information from Historical Data in Clinical Trials
Liyun Jiang, Lei Nie, Ying Yuan
Use of historical data and real-world evidence holds great potential to improve the efficiency of clinical trials. One major challenge is how to effectively borrow information from…