2 citations · 3 across the 4 of their papers we have counts for
4 papers
A modified maximum contrast method for unequal sample sizes in pharmacogenomic studies
Kengo Nagashima, Yasunori Sato, Chikuma Hamada
In pharmacogenomic studies, biomedical researchers commonly analyze the association between genotype and biological response by using the Kruskal--Wallis test or one-way analysis o…
An efficient and robust method for analyzing population pharmacokinetic data in genome-wide pharmacogenomic studies: a generalized estimating equation approach
Kengo Nagashima, Yasunori Sato, Hisashi Noma +1
Powerful array-based single-nucleotide polymorphism--typing platforms have recently heralded a new era in which genome-wide studies are conducted with increasing frequency. A genet…
Adaptive seamless design for establishing pharmacokinetics and efficacy equivalence in developing biosimilars
Ryuji Uozumi, Chikuma Hamada
Recently, numerous pharmaceutical sponsors have expressed a great deal of interest in the development of biosimilars, which requires clinical trials to demonstrate the equivalence…
Interim decision-making strategies in adaptive designs for population selection considering post-progression survival magnitudes
Ryuji Uozumi, Chikuma Hamada
The development of targeted therapies, which benefit only a subgroup of patients treated for a given type of cancer, has been extremely attractive to many investigators. Adaptive s…