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3 papers
A modified maximum contrast method for unequal sample sizes in pharmacogenomic studies
Kengo Nagashima, Yasunori Sato, Chikuma Hamada
In pharmacogenomic studies, biomedical researchers commonly analyze the association between genotype and biological response by using the Kruskal--Wallis test or one-way analysis o…
Sample size calculations for single-arm survival studies using transformations of the Kaplan-Meier estimator
Kengo Nagashima, Hisashi Noma, Yasunori Sato +1
In single-arm clinical trials with survival outcomes, the Kaplan-Meier estimator and its confidence interval are widely used to assess survival probability and median survival time…
An efficient and robust method for analyzing population pharmacokinetic data in genome-wide pharmacogenomic studies: a generalized estimating equation approach
Kengo Nagashima, Yasunori Sato, Hisashi Noma +1
Powerful array-based single-nucleotide polymorphism--typing platforms have recently heralded a new era in which genome-wide studies are conducted with increasing frequency. A genet…