3 papers
stat.ME2023
Ms.FPOP: An Exact and Fast Segmentation Algorithm With a Multiscale Penalty
Arnaud Liehrmann, Guillem Rigaill
Given a time series in with a piecewise constant mean and independent noises, we propose an exact dynamic programming algorithm to minimize a least square criterion with a mu…
q-bio.PE2022
Exponential Integral Solutions for Fixation Time in Wright-Fisher Model With Selection
Vincent Runge, Arnaud Liehrmann, Pauline Spinga
In this work we derive new analytic expressions for fixation time in Wright-Fisher model with selection. The three standard cases for fixation are considered: fixation to zero, to…
q-bio.QM2020
Increased peak detection accuracy in over-dispersed ChIP-seq data with supervised segmentation models
Arnaud Liehrmann, Guillem Rigaill, Toby Dylan Hocking
Motivation: Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromati…