2 papers
q-bio.BM2020
A native chemical chaperone in the human eye lens
Eugene Serebryany, Sourav Chowdhury, Nicki E. Watson +2
Cataract is one of the most prevalent protein aggregation disorders and still the biggest cause of vision loss worldwide. The human lens, in its core region, lacks turnover of any…
q-bio.BM2020
Development of antibacterial compounds that block evolutionary pathways to resistance
Yanmin Zhang, Sourav Choudhury, Joao Rodrigues +1
Antibiotic resistance is a worldwide challenge. A potential approach to block resistance is to simultaneously inhibit WT and known escape variants of the target bacterial protein.…