23 citations · 52 across the 3 of their papers we have counts for
3 papers
physics.bio-ph2020★ 11 cited
Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes
Una Janke, Martin Kulke, Ina Buchholz +3
Integrins are transmembrane proteins involved in hemostasis, wound healing, immunity and cancer. In response to intracellular signals and ligand binding, integrins adopt different…
physics.bio-ph2020★ 23 cited
Lysine residues control the conformational dynamics of beta 2-glycoprotein I
Ina Buchholz, Peter Nestler, Susan Köppen +1
One of the major problems in the study of the dynamics of proteins is the visualization of changing conformations that are important for processes ranging from enzyme catalysis to…
q-bio.BM2020★ 18 cited
The impact of physiological stress conditions on protein structure and trypsin inhibition of serine protease inhibitor Kazal type 1 (SPINK1) and its N34S variant
Ina Buchholz, Felix Nagel, Annelie Klein +6
One of the most common mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene is the N34S variant which is strongly associated with chronic pancreatitis. Although it…