activity
20142022
most citedForce-dependent switch in protein unfolding pathways and transition state movements

68 citations · 147 across the 8 of their papers we have counts for

collaborators
Showing 2014Show all

1 paper · 1 filter

cond-mat.soft2014★ 61 cited

Propensity to form amyloid fibrils is encoded as excitations in the free energy landscape of monomeric proteins

Pavel I. Zhuravlev, Govardhan Reddy, John E. Straub +1

Protein aggregation, linked to many of diseases, is initiated when monomers access rogue conformations that are poised to form amyloid fibrils. We show, using simulations of src SH…