activity
20202026
most citedMachine learning for causal inference: on the use of cross-fit estimators

94 citations · 144 across the 20 of their papers we have counts for

collaborators

21 papers

stat.AP2026

Transporting summary measures of relative effects from randomised trials to the treated patient population: an application to breast cancer endocrine therapy

Bonnie E. Shook-Sa, Paul N. Zivich, Carolyn Taylor +4

Randomised trials often report relative treatment effects, such as risk ratios and hazard ratios, for trial populations. Clinical decision-making, however, often benefits from esti…

stat.OT2026

A Law of Iterated Expectation Primer for Causal Inference

Ashley I. Naimi, Razieh Nabi, Lindsay J. Collin +3

The g-formula is a foundational tool for identifying causal effects in observational data. This tool is based on the law of iterated expectation, a key mathematical identity in sta…

stat.ME2026

Novel g-computation algorithms for time-varying actions with recurrent and semi-competing events

Alena Sorensen D'Alessio, Lucas M. Neuroth, Jessie K Edwards +2

Background: A core aspect of epidemiology is determining the impacts of potential public health interventions over time. With long follow-up periods, epidemiologists may need to co…

stat.OT2025

Unifying Statistical and Mathematical Modeling Through a Causal Inference Lens

Paul N Zivich

Within the biological, physical, and social sciences, there are two broad quantitative traditions: statistical and mathematical modeling. Both traditions have the common pursuit of…

cs.CY2025

Code Sharing in Healthcare Research: A Practical Guide and Recommendations for Good Practice

Lukas Hughes-Noehrer, Matthew J Parkes, Andrew Stewart +8

As computational analysis becomes increasingly more complex in health research, transparent sharing of analytical code is vital for reproducibility and trust. This practical guide,…

stat.ME2025

Confidence Regions for Multiple Outcomes, Effect Modifiers, and Other Multiple Comparisons

Paul N Zivich, Stephen R Cole, Noah Greifer +3

In epidemiology, some have argued that multiple comparison corrections are not necessary as there is rarely interest in the universal null hypothesis. From a parameter estimation p…

stat.ME2025

Constructing g-computation estimators: two case studies in selection bias

Paul N Zivich, Haidong Lu

G-computation is a useful estimation method that can be adapted to address various biases in epidemiology. However, these adaptations may not be obvious for some complex causal str…

math.NT2025

Variants of Romanoff's theorem

Artyom Radomskii

Let and be two sequences of positive integers (not necessarily distinct). Under some restrictions on $…

stat.AP2025

Accounting for Missing Data in Public Health Research Using a Synthesis of Statistical and Mathematical Models

Paul N Zivich, Bonnie E Shook-Sa, Stephen R Cole +2

Introduction: Accounting for missing data by imputing or weighting conditional on covariates relies on the variable with missingness being observed at least some of the time for al…

stat.ME2024

Structural Nested Mean Models Under Parallel Trends with Interference

Zach Shahn, Paul Zivich, Audrey Renson

Despite the common occurrence of interference in Difference-in-Differences (DiD) applications, standard DiD methods rely on an assumption that interference is absent, and comparati…

stat.ME2024

Double Robust Variance Estimation with Parametric Working Models

Bonnie E. Shook-Sa, Paul N. Zivich, Chanhwa Lee +5

Doubly robust estimators have gained popularity in the field of causal inference due to their ability to provide consistent point estimates when either an outcome or exposure model…

stat.ME2023★ 1 cited

Synthesis estimators for positivity violations with a continuous covariate

Paul N Zivich, Jessie K Edwards, Bonnie E Shook-Sa +3

Studies intended to estimate the effect of a treatment, like randomized trials, may not be sampled from the desired target population. To correct for this discrepancy, estimates ca…

stat.ME2023★ 3 cited

Empirical sandwich variance estimator for iterated conditional expectation g-computation

Paul N Zivich, Rachael K Ross, Bonnie E Shook-Sa +2

Iterated conditional expectation (ICE) g-computation is an estimation approach for addressing time-varying confounding for both longitudinal and time-to-event data. Unlike other g-…

stat.AP2023★ 2 cited

Fusing Trial Data for Treatment Comparisons: Single versus Multi-Span Bridging

Bonnie E. Shook-Sa, Paul N. Zivich, Samuel P. Rosin +4

While randomized controlled trials (RCTs) are critical for establishing the efficacy of new therapies, there are limitations regarding what comparisons can be made directly from tr…

stat.ME2023★ 23 cited

Transportability without positivity: a synthesis of statistical and simulation modeling

Paul N Zivich, Jessie K Edwards, Eric T Lofgren +3

When estimating an effect of an action with a randomized or observational study, that study is often not a random sample of the desired target population. Instead, estimates from t…

stat.ME2022★ 4 cited

Positivity: Identifiability and Estimability

Paul N Zivich, Stephen R Cole, Daniel Westreich

Positivity, the assumption that every unique combination of confounding variables that occurs in a population has a non-zero probability of an action, can be further delineated as…

stat.ME2022★ 7 cited

Identifying and estimating effects of sustained interventions under parallel trends assumptions

Audrey Renson, Michael Hudgens, Alexander Keil +2

Many research questions in public health and medicine concern sustained interventions in populations defined by substantive priorities. Existing methods to answer such questions ty…

stat.ME2022★ 1 cited

Bridged treatment comparisons: an illustrative application in HIV treatment

Paul N Zivich, Stephen R Cole, Jessie K Edwards +3

Comparisons of treatments, interventions, or exposures are of central interest in epidemiology, but direct comparisons are not always possible due to practical or ethical reasons.…

stat.ME2022★ 8 cited

Delicatessen: Automated Estimating Equations in Python

Paul N Zivich, Mark Klose, Stephen R Cole +2

Estimating equation theory provides a unified framework for statistical modeling and inference. Applying estimating equations has historically involved extensive matrix algebra and…

stat.ME2020★ 1 cited

Tutorial: Introduction to computational causal inference using reproducible Stata, R and Python code

Matthew J. Smith, Camille Maringe, Bernard Rachet +4

The purpose of many health studies is to estimate the effect of an exposure on an outcome. It is not always ethical to assign an exposure to individuals in randomised controlled tr…

stat.ME2020★ 94 cited

Machine learning for causal inference: on the use of cross-fit estimators

Paul N Zivich, Alexander Breskin

Modern causal inference methods allow machine learning to be used to weaken parametric modeling assumptions. However, the use of machine learning may result in complications for in…