2 papers
q-bio.PE2024
Refining the drift barrier hypothesis: a role of recessive gene count and an inhomogeneous Muller`s ratchet
Luis A. La Rocca, Konrad Gerischer, Anton Bovier +1
The drift-barrier hypothesis states that random genetic drift constrains the refinement of a phenotype under natural selection. The influence of effective population size and the g…
q-bio.PE2020
A lower prevalence for recessive disorders in a random mating population is a transient phenomenon during and after a growth phase
Luis A. La Rocca, Julia Frank, Heidi Beate Bentzen +4
Despite increasing data from population-wide sequencing studies, the risk for recessive disorders in consanguineous partnerships is still heavily debated. An important aspect that…