5 papers
Coupling Anisotropic Curvature and Nematic Order: Mechanisms of Membrane Shape Remodeling
Yoav Ravid, Samo Penič, Luka Mesarec +4
This study theoretically investigates how anisotropic curved membrane components (CMCs) control vesicle morphology through curvature sensing, nematic alignment, topological defects…
Numerical studies of triangulated vesicles with anisotropic membrane inclusions
Yoav Ravid, Samo Penič, Nir Gov +3
In this study, we implement the deviatoric curvature model to examine dynamically triangulated surfaces with anisotropic membrane inclusions. The Monte-Carlo numerical scheme is de…
A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge
Raj Kumar Sadhu, Marine Luciano, Wang Xi +12
Cells often migrate on curved surfaces inside the body, such as curved tissues, blood vessels or highly curved protrusions of other cells. Recent \textit{in-vitro} experiments prov…
Theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces
Raj Kumar Sadhu, Sarah R Barger, Samo Penič +4
Phagocytosis is the process of engulfment and internalization of comparatively large particles by the cell, that plays a central role in the functioning of our immune system. We st…
Modelling cellular spreading and emergence of motility in the presence of curved membrane proteins and active cytoskeleton forces
Raj Kumar Sadhu, Samo Penič, Aleš Iglič +1
Eukaryotic cells adhere to extracellular matrix during the normal development of the organism, forming static adhesion as well as during cell motility. We study this process by con…