331 citations · 408 across the 4 of their papers we have counts for
4 papers
Direct laser writing for cardiac tissue engineering: a microfluidic heart on a chip with integrated transducers
Rachael K. Jayne, M. Çağatay Karakan, Kehan Zhang +6
We have designed and fabricated a microfluidic-based platform for sensing mechanical forces generated by cardiac microtissues in a highly-controlled microenvironment. Our fabricati…
Probing Subcellular Nanostructure of Engineered Human Cardiomyocytes in 3D Tissue
Josh Javor, Jourdan K. Ewoldt, Paige E. Cloonan +9
The structural and functional maturation of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is essential for application to pharmaceutical testing, disease m…
Long Range Force Transmission in Fibrous Matrices Enabled by Tension-Driven Alignment of Fibers
Hailong Wang, Abhilash Nair, Christopher S. Chen +2
Cells can sense and respond to mechanical signals over relatively long distances across fibrous extracellular matrices. Here, we explore all of the key factors that influence long…
Remodeling of Fibrous Extracellular Matrices by Contractile Cells: Predictions from Discrete Fiber Network Simulations
Abhilash Nair, Brendon M. Baker, Britta Trappmann +2
Contractile forces exerted on the surrounding extracellular matrix (ECM) lead to the alignment and stretching of constituent fibers within the vicinity of cells. As a consequence,…