3 papers
physics.bio-ph2026
DNA handles bias force-dependent looping times
Wout Laeremans, Jef Hooyberghs, Wouter G. Ellenbroek
DNA loop formation is a key mechanism in gene regulation, and looping kinetics are sensitive to mechanical tension acting on the DNA. In both single-molecule experiments and biolog…
cond-mat.soft2026
Synthetic design of force-responsive hydrogels with ring-forming catch bonds
Wout Laeremans, Wouter G. Ellenbroek
Catch bonds are interactions whose lifetimes increase under mechanical load, a counterintuitive behaviour that underlies diverse biological processes. Translating this mechanism to…
cond-mat.stat-mech2025
Theoretical Models for Tension-Dependent DNA Looping Time
Wout Laeremans, Wouter G Ellenbroek
The influence of tension on DNA looping has been studied both experimentally and theoretically in the past. However, different theoretical models have yielded different predictions…