8 citations · 9 across the 11 of their papers we have counts for
3 papers · 1 filter
A copula-based set-variant association test for bivariate continuous or mixed phenotypes
Julien St-Pierre, Karim Oualkacha
In genome wide association studies (GWAS), researchers are often dealing with non-normally distributed traits or a mixture of discrete-continuous traits. However, most of the curre…
Weighted asymmetric least squares regression with fixed-effects
Amadou Barry, Karim Oualkacha, Arthur Charpentier
The fixed-effects model estimates the regressor effects on the mean of the response, which is inadequate to summarize the variable relationships in the presence of heteroscedastici…
Detecting differentially methylated regions in bisulfite sequencing data using quasi-binomial mixed models with smooth covariate effect estimates
Kaiqiong Zhao, Karim Oualkacha, Lajmi Lakhal-Chaieb +6
Identifying disease-associated changes in DNA methylation can help to gain a better understanding of disease etiology. Bisulfite sequencing technology allows the generation of meth…